BY SPEAKIN’ OUT NEWS
Dry, itchy skin had long been a frustration during winter, but for people living with atopic dermatitis (AD) — commonly known as eczema — flare-ups became especially disruptive. The chronic inflammatory condition affected up to 20% of children and 3–10% of adults worldwide, making it one of the most widespread skin disorders.
While environmental triggers, allergens and genetics had been well-known contributors, emerging research pointed to an unexpected accomplice: high LDL cholesterol, often referred to as “bad cholesterol.”
A Surprising Link Between Cholesterol and Eczema
New studies suggested that individuals with elevated LDL-C levels faced a significantly higher risk of eczema flare-ups. A 2023 study of more than 1,600 Korean adolescents found that teens with AD had much higher LDL levels (≥130 mg/dL) than their peers. Although weight and hormones influenced risk, researchers said cholesterol levels were the strongest predictor.
People with eczema also showed increased inflammation and lower antioxidant levels, signs that their bodies were under continuous stress at the cellular level.
Why Cholesterol Affected the Skin
The skin’s outer layer — the stratum corneum — relied on a balanced mixture of fats to maintain its barrier. Cholesterol made up nearly a quarter of that layer. When LDL levels rose, the barrier weakened, water escaped more easily and irritants penetrated the skin. This triggered immune overreaction, worsening redness, itching and dryness.
Who Was Most at Risk?
Adolescents, individuals with high blood pressure or type 2 diabetes, and people in perimenopause were more likely to see cholesterol-related skin issues. Sedentary lifestyles and diets high in saturated fat also elevated LDL levels.
Managing Eczema Linked to Cholesterol
Experts recommended:
- Checking LDL levels and aiming for <100 mg/dL
- Following a Mediterranean diet, shown to reduce LDL by up to 15%
- Getting 150 minutes of weekly exercise
- Using ceramide-rich moisturizers to repair the skin barrier
Though eczema remained lifelong for many patients, dermatologists said consistent care and lifestyle adjustments helped most people manage symptoms effectively.